Lives listing with initial: S
- Sadler, John (1615–1674), English political theorist, reformer, college principal
- Sadler, John (fl. 1677–1678), English alchemist
- Sadler, Jonathan (fl. 1797–1799), English painter
- Sage, Balthasar Georges (1740–1824), French chemist
- Sahuguet-Damarzit d'Espagnac, Léonard de (1709–1781), French lawyer, politician
- Saillant, Charles (1716–1786), French printer
- Saingermain, — de (fl. 1680–1685), French physician, alchemist
- Sainsbury, John (c. 1793–1869), English bookseller, author
- Saintard, M. — (fl. 1739), French colonist, author
- Saint-Belin, Marie Françoise de, comtesse de Buffon (1732–1769), French aristocrat
- Sainte-Aldegonde, Philippe Louis Maximilien Ernest Marie Ghislain de, comte de Sainte-Aldegonde (1747–1821), French aristocrat, army officer
- Saint-Félix, Louis Henri Pascal de, baron de Faugères (d. c. 1793), French naval officer, ornithologist
- Saint-George, Armand Louis de, comte de Marsay (1680–1762), French diplomat in British service
- Saint-Georges, Louis Ignace, comte de Foglizzo (fl. 1730), Italian politician
- Saint-Germain, Claude Louis de, comte de Saint-Germain (1707–1778), French soldier, army officer in foreign service, general, government minister in Prussian service
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